Imuran is used for reventing kidney transplant rejection along with other medicine. It may also be used to treat signs and symptoms of active rheumatoid arthritis. It may also be used for other conditions as determined by your doctor.
Use Imuran as directed by your doctor. To avoid stomach upset take Imuran with a meal. Ask your doctor if you should follow any special guidelines for handling Imuran.
Before taking Imuran, tell your doctor or pharmacist if you have any medical conditions, especially if you have allergies to medicines, foods, or other substances, if you are allergic to any ingredient in Imuran, if you have kidney or liver problems, or gout, have an infection, a history of frequent or prolonged infections, or you have recently had a vaccination, have a history of bone marrow problems, anemia, low white blood cell or platelet levels, or unusual bruising or bleeding, if you have certain enzyme deficiencies (thiopurine methyltransferase [TPMT] or xanthine oxidase) or you have recently had a blood transfusion, if you are taking a disease–modifying antirheumatic drug (DMARD) (eg, Methotrexate, adalimumab), if you are pregnant, planning to become pregnant or are breast–feeding. Imuran has been shown to cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imuran while you are pregnant. Imuran is found in breast milk. Do not breast–feed while taking Imuran. Some medicines may interact with Imuran. Therefore tell your doctor of all prescription or nonprescription medicine, herbal preparation, or dietary supplement that you are taking. Do not take Imuran if you have a tumor or an unusual growth, have rheumatoid arthritis and have used alkylating agents (eg, cyclophosphamide, chlorambucil, melphalan) in the past, or if you are taking mercaptopurine. Imuran may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills. Imuran may reduce the number of clot–forming cells in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools. Tell your doctor or dentist that you take Imuran before you receive any medical or dental care, emergency care, or surgery. Talk with your doctor before you receive any vaccine while you are taking Imuran. Contact your doctor at once if you develop severe nausea and vomiting. This may occur with or without diarrhea, rash, fever, muscle pain, or dizziness. If this reaction occurs, it usually happens within the first several weeks of therapy. Imuran may increase your risk of developing a tumor or other cancer. Contact your doctor at once if you notice any unusual growths or lumps. Patients with decreased TPMT enzyme activity may need a lower dose of Imuran. Discuss any questions or concerns with your doctor. Imuran should be used with extreme caution in children. Safety and efficacy in children have not been confirmed.
If you miss a dose take it as soon as you remember. However if it is almost time for the next dose, skip the Missed Dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Possible Side Effects
Some of the Possible Side Effects are– Mild nausea or vomiting. Contact your doctor if any of these or other side effects occur. If you experience any of the following serious side effects, you should seek medical attention immediately– allergic reactions (rash, itching, hives, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue), chest pain or tightness, dark urine, dizziness, fever, chills, or sore throat, increased or painful urination, muscle pain or aches, pale or fatty stools, severe or persistent nausea, vomiting, or diarrhea, shortness of breath, stomach pain, unusual bleeding or bruising, unusual growths or lumps, unusual weakness or fatigue, yellowing of the eyes or skin.
Store Imuran at 68 – 77 °F (20 – 25 °C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Imuran out of the reach of children.
If overdose is suspected seek medical attention immediately. Some of the symptoms of Imuran overdose are– severe or persistent diarrhea, nausea, or vomiting, unusual bruising or bleeding.
Imuran may cause dizziness. These effects may worsen if Imuran is taken with alcohol or certain other medications. Use Imuran with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to this drug. If your symptoms do not improve or if they worsen, contact your doctor. Imuran should be used only by the patient for whom it has been prescribed. Do not take less or more or take it more often than prescribed by your doctor.
This is only general information, it does not cover all directions, drug integrations or precautions. You should not rely on it for any purpose, it does not contain any specific instructions for a particular patient. We disclaim all responsibility for the accuracy and reliability of this information. We`re not responsible for any damage.